Colon cancer

ACA is a 60-year-old patient, who came to us in July 2017 with a diagnosis of stage IV colon cancer, with metastases to the liver and lungs. She had been treated with surgery and chemotherapy. Ten months after starting treatment with Escozul^™ , a tomography examination reports that there are no tumor lesions anywhere in the body.

Case summary:

ACA is a 60-year-old patient, who came to us in July 2017 with a diagnosis of colon cancer metastasized to the liver and lungs treated with surgery and chemotherapy.

When we received the medical documentation, we were able to verify that it was a colon sigmoid cancer initially diagnosed in 2014, specifically a moderately differentiated infiltrating adenocarcinoma, with metastases in the liver and lungs. In a lung biopsy performed in 2017, the disease had evolved into a more aggressive type, being reported as a poorly differentiated adenocarcinoma. This implies a greater ability to grow and metastasize to other organs.

Once the case was analyzed by our specialists, we informed the patient's daughter about what to expect with Escozul^™ and the possibilities of achieving good results.

Each dose of Escozul^™ is personalized, specific to the type of tumor and its aggressiveness. These doses can change over time according to the results that are observed in the patient. For this, effective communication between the patient and our medical team is necessary to allow us to make the appropriate recommendations on different aspects. If the patient or family members do not maintain fluid communication with us then the results with Escozul^™ will not be as expected.

ACA began treatment with Escozul^™ in August 2017, he was undergoing chemotherapy.

Evolution, Monitoring and Current Results:

Communication with Ms. ACA's daughter has been fluid during the treatment time, which is very important in terms of monitoring the results and making the necessary adjustments.

In March 2018 we received a report of a chest X-ray that results without alterations and blood tests that show normal CEA and only one of the slightly elevated transaminases and elevated alkaline phosphatase, although less than in previous studies. He also informs us that clinically he is leading a normal life.

In June 2018, he sent chest, abdomen and pelvic tomography results where no alterations related to the disease were reported, that is, there was no presence of cancer in the studies carried out. The tumor markers CEA and CA 19-9 remain normal and as for the physical condition of the patient they inform us that it is very good.

In this case, the results are very positive, since the joint use of Escozul^™ and chemotherapy has allowed ACA to show no signs of the disease, to have a better life expectancy and to lead a normal life.

As we always say, it is important to note that it is not possible to generalize any results with Escozul^™ to avoid creating false expectations in people, Escozul^™ does not work miracles. Only joint work and constant communication make it possible to maintain personalized and functional doses of Escozul^™ against tumors.

It is also important to say that all the medical information of the case is available to be consulted, as well as the contact with the medical counterpart of both the oncologist who treated the case and our specialists. We believe in transparency in dealing with our patients and the right to form an opinion based on information and analysis.

Finally, in January 2018, after 8 months of treatment with Escozul^™ and 6 chemotherapies, we received the result of the control PET, in which the liver nodules were not observed, nor were the pulmonary nodules and lymph nodes that had previously shown tumor involvement. they are now very small and no longer have tumor activity. In José's words: "I am very happy to see my results, just like the doctors. Thank you for giving me my life expectancy back."

If you wish to be treated under the Escozul^™ Protocol, you should know the following: Escozul^™ is a product that we are still investigating, including its other properties such as analgesic and anti-inflammatory, therefore it is not a commercial product, or be it can not be sold. Each case that wishes to enter our protocol must be evaluated and approved as Escozul^™ is not effective in all types of tumors. Once approved, the patient and their family members must commit to maintaining fluid contact with our medical team.

To enter the protocol, you must send us an email to: servicios@lifescozulcuba.com indicating the age of the patient, the type of cancer and the physical and emotional state of the patient. This is the first step, and a specialist will take care of the case. Our response time is an hour or two, as each case is answered in a personal, non-automatic way. The idea is that the communication we establish is always governed by a professional and humane treatment.

Prepared by the LifEscozul ^™ Group July / 2018

Medical Documents

José is a 51-year-old patient who came to us at the end of 2016, looking for escozul for a relative. Despite being himself an oncology patient, operated on for colorectal cancer with liver metastases, in December 2016, he was without cancer and only undergoing surveillance check-ups. By May 2017, however, he discovered in a checkup that the disease had returned, with metastases in the lungs, lymph nodes and again in the liver, so we analyzed his case and he immediately began with Escozul^™ . After 8 months of using Escozul^™ together with conventional treatments, José's last examination revealed that the disease disappeared!

Case summary:

José started Escozul^™ in May 2017. He had previously suffered from colorectal cancer with liver metastases, which had been treated with chemotherapy and radiotherapy and had surgery. Unfortunately after a few months in follow-up check-ups, it was discovered on tomography that the disease had returned and there were metastases in multiple locations.

When we received the case documents, we were able to verify that José had lymph node involvement in the retroperitoneum, left hepatic and supraclavicular hilum, 4 nodular lesions in the liver, and nodules in both lungs compatible with metastases.

Once the case was analyzed by our specialists, we informed the family what they could expect with Escozul^™ and the possibilities of achieving good results. In cases where the disease reproduces in a short time and there are metastases in multiple locations, the chances of obtaining good results are not the best.

Each dose of Escozul^™ is personalized, specific to the type of tumor and its aggressiveness. These doses can change over time according to the results that are observed in the patient. For this, effective communication between the patient and our medical team is necessary to allow us to make the appropriate recommendations on different aspects. If the patient or family members do not maintain fluid communication with us then the results with Escozul^™ will not be as expected.

José began treatment with Escozul^™ in early May 2017.

Evolution, Monitoring and Current Results:

José is a person who has proven to be positive and determined, with a desire to fight and defeat the disease and has always maintained frequent communication with our medical side and a great discipline in taking the Escozul^™ .

From the first weeks of use of the use of Escozul ^™, he told us that the pain that he had previously presented with colic, and in the spine and head, disappeared and that the intestinal transit was normalized.

José also began receiving chemotherapy and a drug in the monoclonal antibody category.

By August 2017, he had regained 4 kg of weight and reported that the side effects of conventional treatments were very mild and did not last long.

In September, José commented that he was in optimal health with a good quality of life, leading a normal life, working and walking 2 km a day.

In November, José was doing very well and commented that he was following the Escozul^™ treatment to the letter and with a lot of discipline; that she was still very well and that even the doctors were amazed at her general condition and that she had hardly lost any hair and, moreover, had gained weight.

Finally, in January 2018, after 8 months of treatment with Escozul^™ and 6 chemotherapies, we received the result of the control PET, in which the liver nodules were not observed, nor were the pulmonary nodules and lymph nodes that had previously shown tumor involvement. they are now very small and no longer have tumor activity. In José's words: "I am very happy to see my results, just like the doctors. Thank you for giving me my life expectancy back."

In this case, the joint use of Escozul^™ and conventional treatment has been achieved to eliminate the disease. José was able to regain and maintain his quality of life despite chemotherapy and he has a better outlook and life expectancy again.

As we always say, it is important to note that it is not possible to generalize any results with Escozul^™ to avoid creating false expectations in people, Escozul^™ does not work miracles. Only joint work and constant communication make it possible to maintain personalized and functional doses of Escozul^™ against tumors.

It is also important to say that all the medical information of the case is available to be consulted, as well as the contact with the medical counterpart of both the oncologist who treated the case and our specialists. We believe in transparency in dealing with our patients and the right to form an opinion based on information and analysis.

If you wish to be treated under the Escozul^™ Protocol, you should know the following: Escozul^™ is a product that we are still investigating, including its other properties such as analgesic and anti-inflammatory, therefore it is not a commercial product, or be it can not be sold. Each case that wishes to enter our protocol must be evaluated and approved as Escozul^™ is not effective in all types of tumors. Once approved, the patient and their family members must commit to maintaining fluid contact with our medical team.

To enter the protocol, you must send us an email to: servicios@lifescozulcuba.com indicating the age of the patient, the type of cancer and the physical and emotional state of the patient. This is the first step, and a specialist will take care of the case. Our response time is an hour or two, as each case is answered in a personal, non-automatic way. The idea is that the communication we establish is always governed by a professional and humane treatment.

Prepared by the LifEscozul ^™ Group January / 2018

Medical Documents

Concepción is a 73-year-old patient with a history of breast cancer treated with chemotherapy. In February 2017, a new primary tumor was discovered, this time in the lower rectum. After 6 months of treatment, Concepción's exams show no signs of the tumor in the rectum.

Case summary:

We share the case of a 73-year-old patient who came to us in February 2017, with a newly diagnosed lower rectal cancer diagnosis.

When we received the medical documentation, we were able to verify that Concepción had a circumferential tumor from anus to 8cm from the anal margin, determining by biopsy that it was a moderately differentiated, keratinizing, infiltrating and ulcerated squamous cell carcinoma.

Regarding symptoms, she had pain in the anal area, and she was depressed by this diagnosis, considering that she had already fought against breast cancer in the past.

Once the case was analyzed by our specialists, we informed the family what they could expect with Escozul^™ and the possibilities of achieving good results. Concepción's case was discovered in its early stages, when it had not yet spread to other organs, which always means that there are better chances of obtaining good results.

Each dose of Escozul^™ is personalized, specific to the type of tumor and its aggressiveness. These doses can change over time according to the results that are observed in the patient. For this, effective communication between the patient and our medical team is necessary to allow us to make the appropriate recommendations on different aspects. If the patient or family members do not maintain fluid communication with us then the results with Escozul^™ will not be as expected.

Concepción began treatment with Escozul^™ in March 2017. Radiation therapy and oral chemotherapy were pending to begin.

Evolution, Monitoring and Current Results:

Five and a half months after starting the treatment, the new colonoscopy performed in Concepción shows that there is no lesion and that both the colon and the rectal ampulla are normal.

The results in the case of Concepción are excellent, with an early diagnosis and the combination of treatments applied, it has been achieved in less than 6 months to eliminate the disease.

In this case, the indication is to continue treatment with Escozul^™ until completing the first 6 months after the first examination without the presence of tumor cells.

As we always say, it is important to note that it is not possible to generalize any results with Escozul^™ to avoid creating false expectations in people, Escozul^™ does not work miracles. Only joint work and constant communication make it possible to maintain personalized and functional doses of Escozul^™ against tumors.

It is also important to say that all the medical information of the case is available to be consulted, as well as the contact with the medical counterpart of both the oncologist who treated the case and our specialists. We believe in transparency in dealing with our patients and the right to form an opinion based on information and analysis.

If you wish to be treated under the Escozul^™ Protocol, you should know the following: Escozul^™ is a product that we are still investigating, including its other properties such as analgesic and anti-inflammatory, therefore it is not a commercial product, or be it can not be sold. Each case that wishes to enter our protocol must be evaluated and approved as Escozul^™ is not effective in all types of tumors. Once approved, the patient and their family members must commit to maintaining fluid contact with our medical team.

To enter the protocol, you must send us an email to: servicios@lifescozulcuba.com indicating the age of the patient, the type of cancer and the physical and emotional state of the patient. This is the first step, and a specialist will take care of the case. Our response time is an hour or two, as each case is answered in a personal, non-automatic way. The idea is that the communication we establish is always governed by a professional and humane treatment.

Prepared by the LifEscozul ^™ Group September / 2017

Medical Documents

Julia is a 56-year-old patient, who was diagnosed and operated on for colon cancer in 2015. When we received her case in November 2016, she had metastases in the liver and lungs. He came to us looking for a treatment that will help him fight the disease that continued to progress despite being on chemotherapy.

Case summary:

Today we share the case of a 56-year-old patient who came to us in November 2016, with a diagnosis of advanced-stage colon cancer with metastases to the lungs, liver and pelvic node.

When we received the medical documentation, we were able to verify that Julia had a diagnosis of colon cancer, specifically a moderately differentiated adenocarcinoma operated on in 2015, with metastatic tumor lesions in the liver, lungs and pelvic node that appeared in 2016.

Regarding symptoms, she presented discomfort in the right lung area, depression, dizziness and loss of appetite related to chemotherapy.

Once the case was analyzed by our specialists, we informed the patient and her relatives about what they could expect with Escozul^™ and the possibilities of achieving good results. In this case, and given previous experience with similar cases, we hoped at least to help stop the progression of the disease.

Each dose of Escozul^™ is personalized, specific to the type of tumor and its aggressiveness. These doses can change over time according to the results that are observed in the patient. For this, effective communication between the patient and our medical team is necessary to allow us to make the appropriate recommendations on different aspects. If the patient or family members do not maintain fluid communication with us then the results with Escozul^™ will not be as expected.

Julia began treatment with Escozul^™ in December 2016. She was still in chemotherapy irregularly according to the availability of drugs in the hospital.

Evolution, Monitoring and Current Results:

From the first weeks of treatment, Julia showed improvement in terms of symptoms, her relatives informed us that she began to have more appetite and greater energy to carry out her daily activities.

We received the first scan in March 2017, although we did not have anything to specifically compare the results with, since the previous scan was from September 2016 and Julia started her treatment with Escozul^™ in December 2016, so we took this March scan as reference.

By April, Julia's blood tests were all normal, even though she was still receiving chemotherapy.

The CT scan we received dated June 2017 brought us great news. There were no tumor lesions in the chest, abdomen or pelvis. The disease had disappeared.
Julia was leading a normal life without any discomfort and had managed to regain weight.

The October 2017 tomography again shows that no tumor lesions are identified. The family reports that the patient is full of energy and that she has regained 7 kilograms of weight since the treatment began despite chemotherapy.

At this time, Julia continues in treatment with Escozul^™ with increasing doses, seeking to maintain the results obtained.

In this case, it has been possible to eliminate the tumor lesions that it presented in all the affected organs. This result is excellent, as it changes the prognosis of Julia's disease and helps her to lead a normal life in the company of her family.

As we always say, it is important to note that it is not possible to generalize any results with Escozul^™ to avoid creating false expectations in people, Escozul^™ does not work miracles. Only joint work and constant communication make it possible to maintain personalized and functional doses of Escozul^™ against tumors.

It is also important to say that all the medical information of the case is available to be consulted, as well as the contact with the medical counterpart of both the oncologist who treated the case and our specialists. We believe in transparency in dealing with our patients and the right to form an opinion based on information and analysis.

If you wish to be treated under the Escozul^™ Protocol, you should know the following: Escozul^™ is a product that we are still investigating, including its other properties such as analgesic and anti-inflammatory, therefore it is not a commercial product, or be it can not be sold. Each case that wishes to enter our protocol must be evaluated and approved as Escozul^™ is not effective in all types of tumors. Once approved, the patient and their family members must commit to maintaining fluid contact with our medical team.

To enter the protocol, you must send us an email to: servicios@lifescozulcuba.com indicating the age of the patient, the type of cancer and the physical and emotional state of the patient. This is the first step, and a specialist will take care of the case. Our response time is an hour or two, as each case is answered in a personal, non-automatic way. The idea is that the communication we establish is always governed by a professional and humane treatment.

Prepared by the LifEscozul ^™ Group July / 2017

Medical Documents

Luis is a 58-year-old patient, who was diagnosed and operated on for colon cancer in 2014, in 2016 he presented a relapse of the disease in October 2016 with liver metastases that were removed with surgery. He then began receiving chemotherapy, but in January 2017 new liver metastases appeared. He came to us in March 2017 through his wife, seeking a treatment that will help him counter the disease after 3 years of struggle.

Case summary:

We share the case of a 58-year-old patient who came to us in March 2017, with a diagnosis of colon cancer operated with metastasis to the liver. He is a patient who has been in treatment for a very short time, since he has just turned 3 months, but in such a short time very good results have been obtained, because in his last examination the tumors in the liver are no longer seen.

When we received the medical documentation, we were able to verify that Luis had undergone surgery for colon cancer (specifically a well-differentiated adenocarcinoma), which after undergoing surgery in 2014, metastasized to the liver for the first time in October 2016, with compromise of segment VII. left lobe, which was removed by surgery (segmentectomy), and again metastasized to the liver in January 2017, with 3 tumor lesions in the right lobe, between 0.5 and 1.5cm in size.

Once the case was analyzed by our specialists, we informed Luis's wife about what they could expect with Escozul^™ and the possibilities of achieving good results.

Each dose of Escozul^™ is personalized, specific to the type of tumor and its aggressiveness. These doses can change over time according to the results that are observed in the patient. For this, effective communication between the patient and our medical team is necessary to allow us to make the appropriate recommendations on different aspects. If the patient or family members do not maintain fluid communication with us then the results with Escozul^™ will not be as expected.

Luis began treatment with Escozul^™ in March 2017.

Evolution, Monitoring and Current Results:

The case of Luis, to our understanding, has had a rare evolution since well-differentiated carcinomas tend to have less tendency to metastasize. Despite this, Luis has presented metastasis on two occasions, the last time only 3 months after the previous operation.

After the first appearance in 2016 of the liver metastasis that was operated on, Luis started chemotherapy, which did not prevent liver tumors from appearing again in January 2017. According to the family also tells us, the use of chemotherapy has not been continuous, due to variations in the availability of chemotherapy drugs in the health system of your country. After he started Escozul^™ , Luis went two months without chemotherapy, consuming only Escozul^™ .

After 3 months of continuous treatment with Escozul^™ , we received both an ultrasound and a CT scan of the abdomen and pelvis from Luis, in which it was observed that there were no lesions in the liver. The 3 tumor lesions that were previously observed had disappeared.

The new tomography performed at the end of September did not report any obvious complicating alteration, the only elements that are mentioned that are not normal are related to the surgical fingerprint, but no masses or adenopathies are mentioned. Confirm that there is no evidence of disease.

At the moment Luis continues in treatment with Escozul^™ with increasing doses, seeking to maintain the results obtained and help him to have a better quality of life and a better survival expectancy.

As we always say, it is important to note that it is not possible to generalize any results with Escozul^™ to avoid creating false expectations in people, Escozul^™ does not work miracles. Only joint work and constant communication make it possible to maintain personalized and functional doses of Escozul^™ against tumors.

It is also important to say that all the medical information of the case is available to be consulted, as well as the contact with the medical counterpart of both the oncologist who treated the case and our specialists. We believe in transparency in dealing with our patients and the right to form an opinion based on information and analysis.

If you wish to be treated under the Escozul^™ Protocol, you should know the following: Escozul^™ is a product that we are still investigating, including its other properties such as analgesic and anti-inflammatory, therefore it is not a commercial product, or be it can not be sold. Each case that wishes to enter our protocol must be evaluated and approved as Escozul^™ is not effective in all types of tumors. Once approved, the patient and their family members must commit to maintaining fluid contact with our medical team.

To enter the protocol, you must send us an email to: servicios@lifescozulcuba.com indicating the age of the patient, the type of cancer and the physical and emotional state of the patient. This is the first step, and a specialist will take care of the case. Our response time is an hour or two, as each case is answered in a personal, non-automatic way. The idea is that the communication we establish is always governed by a professional and humane treatment.

Prepared by the LifEscozul ^™ Group May / 2017

Medical Documents

Daniel is a 47-year-old patient who was diagnosed with advanced stage rectal cancer. She came to us in early December 2016, through her sister, seeking other treatment options to improve her life prospects with the disease.

Case summary:

The case we share today is about a 47-year-old patient who came to us in early December 2016, with a recent diagnosis of rectal cancer discovered in an advanced stage, when he already had metastases in multiple locations.

When we received the medical documentation, we were able to verify that it was a primary rectal cancer (5.5cm lesion) specifically a moderately differentiated infiltrator) with metastases to the lungs (multiple nodules, the largest of 22mm), liver (36mm secondary lesion), mesorectal fat and right pararectal region, and lymph node (the largest 25mm).

Regarding symptoms, Daniel had back and waist pain, weight loss and was going through a process of depression as a result of the diagnosis of the disease.

Once the case has been analyzed by our specialists, we inform the patient about what to expect with Escozul^™ and the possibilities of achieving good results. In this case, the disease was discovered at a very advanced stage and the chances of obtaining good results were not the best.

Each dose of Escozul^™ is personalized, specific to the type of tumor and its aggressiveness. These doses can change over time according to the results that are observed in the patient. For this, effective communication between the patient and our medical team is necessary to allow us to make the appropriate recommendations on different aspects. If the patient or family members do not maintain fluid communication with us then the results with Escozul^™ will not be as expected.

Daniel began treatment with Escozul^™ in December 2016. He was pending to start chemotherapy

Evolution, Monitoring and Current Results:

In Daniel's case, we started with a very strong dose that is prescribed for very advanced patients.

After three months of treatment and despite being on chemotherapy, Daniel has regained 13 kg of weight (he had lost 40 kg when the disease was diagnosed), his appetite has increased, he has a better face, he has returned to daily activities after several months in who stayed mostly in bed.

On March 23, 2017, a new CT scan was performed, the exact day on which the 3 months of continuous use of Escozul ^{™ were completed} . This new CT scan shows reduction of the largest pulmonary nodule to 20mm (anterior 22mm) and disappearance of the other nodules. The liver injury was reduced to 24mm (mean anterior 36mm). The primary lesion in the rectum was reduced, which is now shown as a slight thickening of the wall, as well as the nodule in mesorectal fat. No node involvement is observed.

In PET / CT of July 2017, it is observed that the rectal lesion remains unchanged with possible inflammatory changes, which means that so far it has not been significantly modified and would be positive because it has not grown. The lung, liver and mesorectal lesions, although they remain metabolically active, have decreased in size, especially those of the liver and lymph nodes, which is also a positive response.

The results in Daniel's case, obtained with the joint use of Escozul^™ and chemotherapy, have been very good for the time he has been in treatment, both at a physical level and at the level of the disease as such. Reduction in size and elimination of tumor lesions has been achieved, despite the poor initial prognosis of the case. These are excellent results that considerably improve Daniel's outlook on life and quality.

We continue the treatment with Escozul^™ with the intention of maintaining and improving the results obtained, to help Daniel to continue fighting with the disease and having a life as normal as possible surrounded by the love of his family.

As we always say, it is important to note that it is not possible to generalize any results with Escozul^™ to avoid creating false expectations in people, Escozul^™ does not work miracles. Only joint work and constant communication make it possible to maintain personalized and functional doses of Escozul^™ against tumors.

It is also important to say that all the medical information of the case is available to be consulted, as well as the contact with the medical counterpart of both the oncologist who treated the case and our specialists. We believe in transparency in dealing with our patients and the right to form an opinion based on information and analysis.

If you wish to be treated under the Escozul^™ Protocol, you should know the following: Escozul^™ is a product that we are still investigating, including its other properties such as analgesic and anti-inflammatory, therefore it is not a commercial product, or be it can not be sold. Each case that wishes to enter our protocol must be evaluated and approved as Escozul^™ is not effective in all types of tumors. Once approved, the patient and their family members must commit to maintaining fluid contact with our medical team.

To enter the protocol, you must send us an email to: servicios@lifescozulcuba.com indicating the age of the patient, the type of cancer and the physical and emotional state of the patient. This is the first step, and a specialist will take care of the case. Our response time is an hour or two, as each case is answered in a personal, non-automatic way. The idea is that the communication we establish is always governed by a professional and humane treatment.

Prepared by the LifEscozul ^™ Group April / 2017

Medical Documents

Initial diagnostic:

Itzvan is a 64-year-old patient, initially diagnosed with colon cancer that was removed by surgery. When he contacted us, he also had metastases in the lung that had not been reduced despite receiving chemotherapy, and in the liver, which had increased in size and number during the administration of chemotherapy.

We received the medical documentation from Itzvan and were able to confirm that the initial diagnosis was colon cancer, specifically intestinal-type infiltrating adenocarcinoma, operated on in June 2016, which metastasized to the lung and liver. He had received chemotherapy and in subsequent follow-up, the nodules in the lung remained the same size, but the nodules in the liver had increased in size and new tumor nodules had appeared.

Once the case has been analyzed by our specialists, we inform the patient about what to expect with Escozul^™ and the possibilities of achieving good results.

Each dose of Escozul^™ is personalized, specifying the type of tumor and its aggressiveness. These doses can change over time according to the results that are observed in the patient. For this, effective communication between the patient and our medical team is necessary to allow us to make the appropriate recommendations on different aspects. If the patient or family members do not maintain fluid communication with us then the results with Escozul^™ will not be as expected.

Itzvan began treatment with Escozul^™ in December 2016, while continuing chemotherapy.

Evolution and current results:

Itzvan began receiving Escozul^™ on a regular basis since December 2016. She had her first control examination in the first days of March 2017. The results show that the disease at the lung level remains stable. The great surprise came when reviewing the results obtained at the liver level: both the inflammation of the liver and the tumor lesions in it have decreased in size, with the largest nodule decreased by 22%.

This is a very important result, because before starting Escozul^™ , despite receiving chemotherapy for 6 months, the nodules in the liver had increased and new nodules had appeared.

By introducing the use of Escozul^™ , it has been possible to control and reduce the disease at the liver level over the course of 3s months, which is very positive for the evolution of the patient, despite the fact that the disease is still advanced and There is still much left to do.

These results open a door of hope that encourages the patient and their family members to continue fighting.

As we always say, it is important to note that it is not possible to generalize any results with Escozul^™ to avoid creating false expectations in people, Escozul^™ does not work miracles. Only joint work and constant communication make it possible to maintain personalized and functional doses of Escozul^™ against tumors.

It is also important to say that all the medical information of the case is available to be consulted, as well as the contact with the medical counterpart of both the oncologist who treated the case and our specialists. We believe in transparency in dealing with our patients and the right to form an opinion based on information and analysis.

If you wish to be treated under the Protocol with Escozul ^{™ you} should know the following: Escozul^™ is a product that we are still investigating, including its other properties such as analgesic and anti-inflammatory, therefore it is not a commercial product, or be it can not be sold. Each case that wishes to enter our protocol must be evaluated and approved as Escozul^™ is not effective in all types of tumors. Once approved, the patient and their family members must commit to maintaining fluid contact with our medical team.

To enter the protocol, you must send us an email to: servicios@lifescozulcuba.com indicating the age of the patient, the type of cancer and the physical and emotional state of the patient. This is the first step, and a specialist will take care of the case. Our response time is an hour or two, as each case is answered in a personal, non-automatic way. The idea is that the communication that we establish is always governed by a professional and humane treatment.

Prepared by the LifEscozul ^™ Group March / 2017

Medical Documents

Initial diagnostic:

Colon cancer operated in 2012. Lymph node metastasis in the neck, left armpit, and iliac and inguinal chains, in the mediastinum in the right paravertebral solid tissue at T10 level, in bone structures (left humerus, left sacrum, left acetabulum, left ischiopubic branch).

Initial symptoms:

• pain in the right shoulder

• loss of appetite secondary to chemotherapy

• irregular night's rest

• occasional headache

• nausea

• threw up

• anemia

Treatments:

She started Escozul^™ in February 2015. The patient was undergoing chemotherapy treatment with adverse effects of importance for the quality of life.

It is important to remember that Escozul^™ is a natural product that has the ability to kill tumor cells, without this meaning that it is a cure for cancer. Its ability to inhibit malignant cell growth allows it to be used as a disease controller and the work approach is carried out seeking that the patient can live with their disease with the least possible impact on their daily routine.

Evolution and current results:

From the beginning of treatment, the patient reports improvement of symptoms secondary to chemotherapy. After a month and a half of treatment, this improvement is reflected in the blood tests, where it is evidenced that there is no longer anemia, the patient's hemoglobin is in the normal range.

At the end of May, 3 and a half months after starting treatment, his physical condition is referred to as stable. A full-body PET / CT study shows that lymph node metastases have decreased in size: in the neck from 14mm to 11mm, left armpit from 18mm to 15mm, iliac chains from 23mm to 19mm and in the groin from 23 to 16mm; no involvement in the mediastinum is observed, bone metastases are stable, metastasis in the humerus is not observed.

In July the patient reported feeling good in health, without major discomfort. The oncologist stopped chemotherapy, and the patient is alone with Escozul^™ , natural antioxidant remedies, and a healthy diet.

In this case, it has been possible to improve the quality of the patient, and to keep the disease under control, with a reduction in the size of the metastases and some
metastatic locations. These results contribute to a higher quality patient survival, which is very important for any cancer patient, not only to continue living, but to feel good and to be able to lead a practically normal life.

It is important to note that it is not possible to generalize any results with Escozul^™ to avoid creating false expectations in people. Each case we receive is analyzed seeking to inform the family what to expect from it. Each person is a completely different universe from another even if they have the same disease. This writing does not constitute a testimony but a summary of evolution where medical information is available to consult.

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First steps:

When Carlos came to us the doctors had recommended palliative chemotherapy.

Our first step is always to know the case in depth and for this we carry out an evaluation of the patient where several aspects are determined such as:

• - Personalized dosage and concentration.
• - Comparison with other cases with the same type of tumor and results.
• - Analysis of the patient's physical and emotional state.

Contact with the patient:

Then the patient and family members are informed about what they can expect from Escozul^™ and the importance of maintaining contact with our specialists that allows the dose to be changed when necessary, in order to obtain the best possible results.

Carlos started Escozul^™ at the end of January 2014, jointly receiving palliative chemotherapy.

It is important to remember that Escozul^™ is a natural product that has the ability to kill tumor cells, without this meaning that it is a cure for cancer. Its ability to inhibit malignant cell growth allows it to be used as a disease controller and the work approach is carried out seeking that the patient can live with their disease with the least possible impact on their daily routine.

Evolution:

In April 2014, the first CT scan was performed, which showed an 18% reduction in the primary lesion, as well as a decrease in size in the
secondary locations in the lung and liver. By that time the patient did not present abdominal pain.

This result had a positive impact on their quality of life. At 6 months of treatment, the CT scan showed a further reduction in the colorectal lesion,
stability of the lesions at the lung level and disappearance of one of the liver lesions.

After one year of treatment, the disease remained controlled and with reductions in certain areas. Carlos's quality of life had improved a lot.

In June 2015, more positive news arrived, a new CT scan shows the disappearance of liver lesions. The primary tumor remained stable and there was a slight increase in size in some lung lesions. Faced with this increase, the concentration of the Escozul^™ dose was again increased .

In December 2015, the situation remained stable, in addition to maintaining the patient in good physical condition and with a good quality of life. This represents
a considerable increase in the survival time initially estimated for the patient. It is also valid to point out that Carlos went through different chemotherapy cycles with few adverse effects and good tolerance, something common in patients taking Escozul^™ in conjunction with conventional therapies. Carlos has followed the Escozul^™ treatment with progressive dose increases, seeking to maintain and improve these results.

As we always explain to our patients, Escozul ^{™ is} not considered a cure for cancer, at this time it has been possible to keep the disease under control and that the patient can live with cancer leading a practically normal life.

Carlos has been with us for almost two years and in the words of his son here is a summary:

“Indeed, the results have actually been very good, since the liver tumors have disappeared and the colon, which is the origin of the disease, also decreased its volume significantly, so if we manage to at least reduce the size of the lung, we would be in a clear way to give my father a good time to live. I take the opportunity to thank them for their good disposition and the support given in almost two years now, they are a very serious working group. "

It is important to note that it is not possible to generalize any results with Escozul^™ to avoid creating false expectations in people. Each case we receive is analyzed seeking to inform the family what to expect from it. Each person is a completely different universe from another even if they have the same disease. This writing does not constitute a testimony but a summary of evolution where medical information is available to consult.

Medical Documents

Initial diagnostic:

Stage IV colon cancer (moderately differentiated tubular adenocarcinoma, partly ulcerated), metastases to liver and lungs, CEA (carcinoembryonic antigen) = 303 (normal value up to 3.4)

Initial symptoms:

Pain in the abdomen at the level of the liver and chest

Treatments:

It began with Escozul^™ in January 2015. It was pending to start with the application of palliative chemotherapy, which began in February 2015. Escozul^™ is a natural product that has the ability to eliminate tumor cells without this meaning that it is a cure for cancer. Its ability to inhibit malignant cell growth allows it to be used as a disease controller and the work approach is carried out seeking that the patient can live with their disease with the least possible impact on their daily routine.

Evolution and current results:

The first control exams were received in March 2015, two months after starting Escozul^™ . The CEA in mid-March had decreased from
an initial value of 303, to 203, at the end of March it dropped to 145.

In April 2015, after three months of treatment, the CEA value was 86. In CT of the chest, abdomen and pelvis, a decrease in the size of liver metastases, lower density of lung metastases, stability in tumor remnant in colon. The patient does not report symptoms except for the discomforts associated with chemotherapies.

CT was repeated in May 2015, which shows a new decrease in liver and lung metastases and stability of tumor lesions in the colon. The CEA tumor marker in May had decreased to 33.4.

In July the CT scan was repeated, showing that metastases in the liver and lung continued to decrease, and the lesions in the colon were stable. The score on this occasion was 19.7.

The patient is in good physical condition, leading a normal life. The results obtained in this case are important, as it is achieved, in conjunction with chemotherapy, to gradually decrease the cancer activity in the body and eliminate tumor cells, which is reflected in the decrease in the size of the metastases and in the control of the disease at the primary location; in addition to keeping the patient with a good quality of life.

The results in this case reinforce that the administration of Escozul^™ in conjunction with conventional treatments can be very positive not only in terms of symptom management but also in terms of obtaining results.

Initial diagnostic:

High-grade colon cancer operated on, with metastases to the liver, omentum and jejunum. Tumor marker CA19-9 = 1183 (normal value: up to 37)

Initial symptoms:

Loss of appetite

• - Weightloss
• - fatigue
• - Reflux

Escozul^™ treatments :

He started with Escozul^™ at the end of June 2014. He was undergoing chemotherapy treatment with the aforementioned symptoms due to the disease and the treatment.

Escozul ^™ is a natural product that has the ability to kill tumor cells, without meaning that it is a cure for cancer. Its ability to inhibit malignant cell growth allows it to be used as a disease controller and the work approach is carried out seeking that the patient can live with their disease with the least possible impact on their daily routine.

Evolution and current results:

Within a week of starting treatment, her appetite began to improve despite chemotherapy. 24 days after starting Escozul^™ , her appetite was still better, her mood had improved and her fatigue had decreased. In September 2014, we are informed that she has been stable with no relapse in her symptoms.

In October 2014, the tumor marker decreased to 25 (within normal limits). The rest of the time the patient has been stable.

In March 2015, after 7 and a half months of treatment with Escozul^™ , together with chemotherapy, the tumor marker remains within normal limits, at 37. The
patient maintains a good appetite, good spirits and has regained weight.

The March abdominal pelvic CT results did not show evidence of tumor or metastatic activity. The patient continues to consume Escozul^™ with progressive doses in order to maintain these results.

In this case, it has been possible to improve the quality of life of the patient, and eliminate metastases, which began to be seen in the reduction of the value of the tumor antigen.

The patient is leading a normal life with her family, without the disease affecting her activities and physical and mental well-being.

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