Research and Development

Mariela Guevara
Dr. Mariela Guevara is the Senior Advisor for the LifEscozul™ Group's Clinical Trials to be developed in 2021.
As part of the Health Registration process, she is the person in charge of preparing the protocols associated with the trials and their control.
Dr. Mariela Guevara has a vast experience in the management of clinical trial protocols enriched with more than 10 years working on the blue scorpion venom issue.
STUDIES
2015 - 2016Master in Translational Research and Clinical Trials. University of Extremadura. Spain.
2007 - 2008Diploma in Oxidative Stress. Health and disease. Institute of Pharmacy and Food. University of Havana. Cuba.
2003Second Degree Specialist in Pharmacology. At the Facultad Docente Salvador Allende Higher Institute of Medical Sciences of the University of Havana.
1997First Degree Specialist in Pharmacology. At the Facultad Docente Calixto García Higher Institute of Medical Sciences of the University of Havana.
1991Doctor of Medicine at the Finlay - Albarrán Faculty, Higher Institute of Medical Sciences of the University of Havana.
WORK EXPERIENCE
2019 - CurrentAdvisor for clinical trials for Lifescozul Group™ Chile SpA. - Chile.


Pharmaceutical
1998 - 2009Pharmacological Research Group. Center of Pharmaceutical Chemistry. Cuba.
1991 - 1997Resident of Clinical and Experimental Pharmacology. University of Havana. Cuba.
Teaching
Professor - researcher of the Faculty of Health Sciences. Pedro Henríquez Ureña National University. (UNPHU). Dominican Republic.
Assistant Professor of Pharmacology and Physiology. Faculty of Medicine No. 3 Finlay - Albarrán.
Universidad de La Habana, Cuba.
Subjects taught:
- - General Physiology.
- - General Pharmacology and Toxicology, undergraduate and graduate (residents).
- - Research Methodology
RESEARCH AND DEVELOPMENT
2009 - 2016- - Clinical studies on the use of an extract of Mangifera indica L. (Vimang) in inflammatory and oxidative stress states.
- - Quality of clinical research.
- - Research to automate databases in laboratories of sites participating in Clinical Trials.
- - Clinical trials on the use of Ferrical as an antianemic.
- - Clinical trials on the use of Nutrisol in nutritional disorders.
- - Development of dossier for authorization to start a clinical trial with RLN-01 (Rophalurus junceus scorpion venom).
2004 - 2008
Head of Project of the Ministry of Science, Technology and Environment of Cuba (CITMA): Evaluation of the effect of a natural extract of Mangifera indica L. on diseases related to oxidative stress: Ischemic Cerebrovascular Disease and Diabetes Mellitus Type I.
2003 - 2009Head Project of the Ministry of Public Health of Cuba (MINSAP) Evaluation of the effect of an extract of Mangifera indica L. in spinocerebellar ataxia type 2. Oxidative stress and neurophysiological studies in ataxic patients type SCA2.
2002 - 2003Evaluation of the effect of Vimang supplementation on indicators of oxidative stress and disease progression in HIV/AIDS patients..
1998 - 2008Pharmacological studies of natural extracts with biological activity. Oxidative stress and inflammation. Main mediators. In vitro and in vivo biological models.
MEMBERSHIP IN SCIENTIFIC SOCIETIES
2009 - 2016- - Founding member of the Cuban Society of Pharmacology.
- - Member of the Cuban Society of Pharmacy.
- - Full member of the Spanish Society of Pharmacology.

AWARDS
Investigador Titular. MESCYT.
PREMIO NACIONAL DE FARMACOLOGÍA: Caracterización de variables de estrés oxidativo en diferentes condiciones clínicas.
PREMIO LATINOAMERICANO DE FARMACOLOGÍA DR. PLUTARCO NARANJO IN MEMORIAN: Caracterización de variables de estrés oxidativo en diferentes condiciones clínicas.
PREMIO SOCIEDAD CUBANA DE FARMACOLOGÍA: Mención modalidad reviews (Artículos Científicos de Revisiones Temáticas). The paradox of natural products as pharmaceuticals. Experimental evidences of a mango stem bark extract. (Publicado en: Pharmacological Research 55: 351–358, 2007).
III International Congress Health science CICS-UDABOL, Bolivia. "Potentialities of RjLB-14 peptide for anticancer treatment." (conference).
MAIN INTERNATIONAL PUBLICATIONS
Ver másPUBLICATIONS IN BOOKS WITH EDITORIAL BOARD
“Vimang: Experiences from the Antioxidant Therapy in Cuban Primary Health Care” en V.K. Gupta, A.K. Verma (Eds.) Comprehensive Bioactive Natural Products Studium Press, Houston. Vol. IV, Ch. 14, p. 259-71, ISBN 1-933699-54.
EL RETO EN LA TERAPIA ANTIOXIDANTE. LIBRO. Editorial Científico-Técnica. Cuba. ISBN 978-959-05-0525-6.
Recent advances in the research & development of and aqueous stem bark extract from Mangifera indica L. In: Recent Developments in Medicinal Plant Research, Editor: Anna Capaso, Research Signpost, Kerala, India, (ISBN: 978-81-308-0160), pp. 169-192.
PARTICIPATION WITH EXHIBITION OF WORKS IN INTERNATIONAL EVENTS
LANGUAGES
Spanish - Native
English - Intermediate